Table 1

Melanoma tumors have more gross necrosis in CIB1-KO mice.

Mouse Genotype

Total Number of Mice

Mice with Tumor Necrosis

Mice with No Tumor Necrosis

% of Mice with Tumor Necrosis


B16 Melanoma Tumorsa

WT

9

3

6

33.3%

CIB1-KO

11

7

4

63.6%b


Lewis Lung Carcinoma Tumors

WT

8

0

8

0.0%

CIB1-KO

9

0

9

0.0%c


aTumor necrosis was grossly evident in B16 melanoma tumors that developed in both WT and CIB1-KO mice.

bThe number of tumors with clear evidence of gross necrosis in CIB1-KO mice was statistically significant (p = 0.05), chi-square test with one degree of freedom.

cThere was no evidence of gross necrosis in Lewis lung carcinoma tumors that developed in both WT and CIB1-KO mice.

Zayed et al. Journal of Angiogenesis Research 2010 2:17   doi:10.1186/2040-2384-2-17

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