Table 1 |
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|
Melanoma tumors have more gross necrosis in CIB1-KO mice. |
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|
Mouse Genotype |
Total Number of Mice |
Mice with Tumor Necrosis |
Mice with No Tumor Necrosis |
% of Mice with Tumor Necrosis |
|
|
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|
B16 Melanoma Tumorsa |
||||
|
WT |
9 |
3 |
6 |
33.3% |
|
CIB1-KO |
11 |
7 |
4 |
63.6%b |
|
|
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|
Lewis Lung Carcinoma Tumors |
||||
|
WT |
8 |
0 |
8 |
0.0% |
|
CIB1-KO |
9 |
0 |
9 |
0.0%c |
|
|
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|
aTumor necrosis was grossly evident in B16 melanoma tumors that developed in both WT and CIB1-KO mice. bThe number of tumors with clear evidence of gross necrosis in CIB1-KO mice was statistically significant (p = 0.05), chi-square test with one degree of freedom. cThere was no evidence of gross necrosis in Lewis lung carcinoma tumors that developed in both WT and CIB1-KO mice. |
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|
Zayed et al. Journal of Angiogenesis Research 2010 2:17 doi:10.1186/2040-2384-2-17 |
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