Figure 4.

Effects of R1-mAb and R2-mAb on the in-vitro apoptosis and caspase-3 activity of EC. A: The R1-mAb and R2-mAb significantly increased the apoptotic index induced by Gal-N+LPS. The effect of R2-mAb on the apoptotic index was also more potent than R1-mAb. The effects of mAbs on the caspase-3 were almost in parallel with the augmentation of the apoptotic index (B). Cont: Control IgG-treated group. R1and R2: R1-mAb- and R2-mAb-treated group, respectively. The data represents the mean ± SD (n = 6). *: Statistically significant differences between the experimental groups (p < 0.05).