Table 1

Specificity of the n-3 PUFA effect on cell migration

Treatment

Wound width (μm)

Medium

852 ± 15

Vehicle (ethanol)

905 ± 118 ns

PUFA EE

1166 ± 94 **

DHA EE

896 ± 51 ns

EPA EE

1189 ± 60 **

DHA EE + EPA EE

1156 ± 9 **

Confluent EC monolayers were wounded and treated with the indicated compound (each at a concentration of 100 μM) for 24 hours before being fixed and inspected by fluorescence microscopy to quantitate the wound width. The initial width (at time 0) measured 1194 ± 7 μm. Data are means ± SD from three different experiments (each performed in duplicate). **p < 0.01; ns not significant (compared with medium).

Tonutti et al. Journal of Angiogenesis Research 2010 2:12   doi:10.1186/2040-2384-2-12